BDBM764973 3-((8-oxabicyclo[3.2.1]octan-3-yl)(ethyl) amino)-5-(trans-3-(cis-2,6-dimethylmorpholinyl)cyclobutoxy)-N-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methylbenzamide::US12390472, Example 88

SMILES CCN(c1cc(O[C@H]2C[C@H](N3C[C@@H](C)O[C@@H](C)C3)C2)cc(C(=O)NCc2c(OC)cc(C)[nH]c2=O)c1C)C1CC2CCC(C1)O2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 764973   

LigandPNGBDBM764973(3-((8-oxabicyclo[3.2.1]octan-3-yl)(ethyl) amino)-5...)
Affinity DataIC50: 1.10nMAssay Description:Table 1: Test ConditionsEZH2 enzyme complex: 25 ng/uLHistone H3 peptide substrate: 4 uMSAM: 2 uMReaction time: 300 minProcedures1. Each compound disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM764973(3-((8-oxabicyclo[3.2.1]octan-3-yl)(ethyl) amino)-5...)
Affinity DataIC50: 2nMAssay Description:ProceduresCompounds at different concentrations were dissolved in 100% DMSO and transferred to test plates, and the final concentration of DMSO was 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM764973(3-((8-oxabicyclo[3.2.1]octan-3-yl)(ethyl) amino)-5...)
Affinity DataIC50: 3.30nMAssay Description:Table 4: ProceduresCompounds at different concentrations were dissolved in 100% DMSO and transferred to test plates, and the final concentration of D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent