BDBM766107 US20250263426, Compound 76-1

SMILES O=[S@@]1CCc2nc(N3CC4CN(c5ccc6c(c5)CC6)CC4C3)nc(Nc3cccc(F)c3)c21

InChI Key InChIKey=QTYGMPMGXFLDNF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 766107   

Target3',5'-cyclic-AMP phosphodiesterase 4B2 (PDE4B2)(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 766107BDBM766107(US20250263426, Compound 76-1)
Affinity DataIC50: 10nMAssay Description:The effect of compounds on PDE4B2 activity was detected using a fluorescence polarization kit (BPS Bioscience, Catalog #60343). According to the inst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/3/2025
Entry Details
US Patent

TargetIsoform 2 of 3',5'-cyclic-AMP phosphodiesterase 4D(Homo sapiens (Human))
Xizang Haisco Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 766107BDBM766107(US20250263426, Compound 76-1)
Affinity DataIC50: 30nMAssay Description:The effect of compounds on PDE4D2 activity was detected using a fluorescence polarization kit (BPS Bioscience, Catalog #60345). During the reaction, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/3/2025
Entry Details
US Patent