BDBM766108 US20250263426, Compound 77-1

SMILES O=S6CCc5nc(N2CC=C(c1ncc(Cl)cn1)CC2)nc(N3CC[C@H](CO)C34CCC4)c56

InChI Key InChIKey=JGMMJOMWXHVDKC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 766108   

Target3',5'-cyclic-AMP phosphodiesterase 4B2 (PDE4B2)(Human)
Xizang Haisco Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 766108BDBM766108(US20250263426, Compound 77-1)
Affinity DataIC50: 10nMAssay Description:The effect of compounds on PDE4B2 activity was detected using a fluorescence polarization kit (BPS Bioscience, Catalog #60343). According to the inst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/3/2025
Entry Details
US Patent

TargetIsoform 2 of 3',5'-cyclic-AMP phosphodiesterase 4D(Homo sapiens (Human))
Xizang Haisco Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 766108BDBM766108(US20250263426, Compound 77-1)
Affinity DataIC50: 10nMAssay Description:The effect of compounds on PDE4D2 activity was detected using a fluorescence polarization kit (BPS Bioscience, Catalog #60345). During the reaction, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/3/2025
Entry Details
US Patent