BDBM768420 4-((4-([1,2,4]triazolo[1,5- a]pyridin-7-yloxy)-3- methylphenyl)amino)-N- (3-(dimethylamino)- propyl)pyrrolo[2,1- f][1,2,4]triazine-5- carboxamide::US20250276983, Example 178

SMILES Cc1cc(Nc2ncnn3ccc(C(=O)NCCCN(C)C)c23)ccc1Oc1ccn2ncnc2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 768420   

TargetReceptor tyrosine-protein kinase erbB-2 [1-775,'YVMA',776-1255](Human)
Iambic Therapeutics

US Patent
LigandPNGBDBM768420(4-((4-([1,2,4]triazolo[1,5- a]pyridin-7-yloxy)-3- ...)
Affinity DataIC50: 200nMAssay Description:The radioactive signal generated from the aliquot of buffer solution was proportional to the amount of radiolabeled substrate produced, and which is ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Iambic Therapeutics

US Patent
LigandPNGBDBM768420(4-((4-([1,2,4]triazolo[1,5- a]pyridin-7-yloxy)-3- ...)
Affinity DataIC50: 200nMAssay Description:The radioactive signal generated from the aliquot of buffer solution was proportional to the amount of radiolabeled substrate produced, and which is ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Iambic Therapeutics

US Patent
LigandPNGBDBM768420(4-((4-([1,2,4]triazolo[1,5- a]pyridin-7-yloxy)-3- ...)
Affinity DataIC50: 1.00E+3nMAssay Description:The radioactive signal generated from the aliquot of buffer solution was proportional to the amount of radiolabeled substrate produced, and which is ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/15/2025
Entry Details
US Patent