BDBM7689 4-[N'-(4-Iodo-2-oxo-1,2-dihydro-indol-3-ylidene)-hydrazino]benzenesulfonamide::4-{2-[(3Z)-4-iodo-2-oxo-2,3-dihydro-1H-indol-3-ylidene]hydrazin-1-yl}benzene-1-sulfonamide::Oxindole-Based Inhibitor 25

SMILES NS(=O)(=O)c1ccc(NN=C2C(=O)Nc3cccc(I)c23)cc1

InChI Key InChIKey=YYLOHWVUZJXESM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 7689   

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Glaxosmithkline

LigandPNGBDBM7689(4-[N'-(4-Iodo-2-oxo-1,2-dihydro-indol-3-ylidene)-h...)
Affinity DataIC50: 4.60nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2006
Entry Details Article
PubMed
LigandPNGBDBM7689(4-[N'-(4-Iodo-2-oxo-1,2-dihydro-indol-3-ylidene)-h...)
Affinity DataIC50: 110nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2006
Entry Details Article
PubMed