BDBM770274 N-((3S,4S)-4-(3-chlorophenyl)-1-(imidazo[1,5-a]pyridine-8-carbonyl)piperidin-3-yl)-4, 7-difluoro-1H-benzo[d]imidazole-2-carboxamide::WO2024107778, Compound 59

SMILES O=C(N[C@@H]1CN(C(=O)c2cccn3cncc23)CC[C@H]1c1cccc(Cl)c1)c1nc2c(F)ccc(F)c2[nH]1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 770274   

TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Pharmaceutical

WIPO
LigandChemical structure of BindingDB Monomer ID 770274BDBM770274(N-((3S,4S)-4-(3-chlorophenyl)-1-(imidazo[1,5-a]pyr...)
Affinity DataIC50: 17.8nMAssay Description: Compounds are 3 fold serially diluted for 10 doses and added to an assay plate (384w format) using ECHO, in duplicate wells. The test concentration ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2024107778

TargetAngiotensin-converting enzyme 2(Human)
Takeda Pharmaceutical

WIPO
LigandChemical structure of BindingDB Monomer ID 770274BDBM770274(N-((3S,4S)-4-(3-chlorophenyl)-1-(imidazo[1,5-a]pyr...)
Affinity DataEC50:  88.4nMAssay Description: Compounds are 3 fold serially diluted for 10 doses and added to an assay plate (384w format) using ECHO, in duplicate wells. The test concentration ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2024107778