BDBM770457 (R)-N-((3S,4S)-4-(3-chloro-5-fluorophenyl)-1-(imidazo[1,5-a]pyridine-8-carbonyl)piperidin-3-yl)-2-methylpyrrolidine-2-carboxamide::WO2024107778, Compound 266

SMILES C[C@]1(C(=O)N[C@@H]2CN(C(=O)c3cccn4cncc34)CC[C@H]2c2cc(F)cc(Cl)c2)CCCN1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 770457   

TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Pharmaceutical

WIPO
LigandChemical structure of BindingDB Monomer ID 770457BDBM770457((R)-N-((3S,4S)-4-(3-chloro-5-fluorophenyl)-1-(imid...)
Affinity DataIC50: 48.6nMAssay Description: Compounds are 3 fold serially diluted for 10 doses and added to an assay plate (384w format) using ECHO, in duplicate wells. The test concentration ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2024107778

TargetAngiotensin-converting enzyme 2(Human)
Takeda Pharmaceutical

WIPO
LigandChemical structure of BindingDB Monomer ID 770457BDBM770457((R)-N-((3S,4S)-4-(3-chloro-5-fluorophenyl)-1-(imid...)
Affinity DataEC50:  172nMAssay Description: Compounds are 3 fold serially diluted for 10 doses and added to an assay plate (384w format) using ECHO, in duplicate wells. The test concentration ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2024107778