BDBM770469 N-((3S,4S)-4-(3-chloro-5-fluorophenyl)-1-(imidazo[1,5-a]pyridine-8-carbonyl)piperidin-3-yl)-2-(4-azaspiro[2.4]heptan-4-yl)acetamide::WO2024107778, Compound 278

SMILES O=C(CN1CCCC12CC2)N[C@@H]1CN(C(=O)c2cccn3cncc23)CC[C@H]1c1cc(F)cc(Cl)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 770469   

TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Pharmaceutical

WIPO
LigandChemical structure of BindingDB Monomer ID 770469BDBM770469(N-((3S,4S)-4-(3-chloro-5-fluorophenyl)-1-(imidazo[...)
Affinity DataIC50: 63.0nMAssay Description: Compounds are 3 fold serially diluted for 10 doses and added to an assay plate (384w format) using ECHO, in duplicate wells. The test concentration ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2024107778

TargetAngiotensin-converting enzyme 2(Human)
Takeda Pharmaceutical

WIPO
LigandChemical structure of BindingDB Monomer ID 770469BDBM770469(N-((3S,4S)-4-(3-chloro-5-fluorophenyl)-1-(imidazo[...)
Affinity DataEC50:  182nMAssay Description: Compounds are 3 fold serially diluted for 10 doses and added to an assay plate (384w format) using ECHO, in duplicate wells. The test concentration ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2024107778