BDBM770470 (R)-N-((3S,4S)-4-(3-chloro-5-fluorophenyl)-1-(imidazo[1,5-a]pyridine-5-carbonyl)piperidin-3-yl)-2-hydroxy-3,3-dimethylbutanamide::WO2024107778, Compound 279

SMILES CC(C)(C)[C@@H](O)C(=O)N[C@@H]1CN(C(=O)c2cccc3cncn23)CC[C@H]1c1cc(F)cc(Cl)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 770470   

TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Pharmaceutical

WIPO
LigandChemical structure of BindingDB Monomer ID 770470BDBM770470((R)-N-((3S,4S)-4-(3-chloro-5-fluorophenyl)-1-(imid...)
Affinity DataIC50: 32.0nMAssay Description: Compounds are 3 fold serially diluted for 10 doses and added to an assay plate (384w format) using ECHO, in duplicate wells. The test concentration ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2024107778

TargetAngiotensin-converting enzyme 2(Human)
Takeda Pharmaceutical

WIPO
LigandChemical structure of BindingDB Monomer ID 770470BDBM770470((R)-N-((3S,4S)-4-(3-chloro-5-fluorophenyl)-1-(imid...)
Affinity DataEC50:  69nMAssay Description: Compounds are 3 fold serially diluted for 10 doses and added to an assay plate (384w format) using ECHO, in duplicate wells. The test concentration ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2024107778