BDBM771455 (3S)-6-chloro-2''-(5-chloro-2- fluorophenyl)-5''-(2,4- dimethoxypyrimidin-5-yl)-6''- (propan-2-yl)-1,2,3'',5''- tetrahydro-2''H-spiro[indole- 3,1''-pyrrolo[3,4-c]pyrrole]-2,3''- dione::US12415811, Compound 2

SMILES COc1ncc(-n2cc3c(c2C(C)C)[C@@]2(C(=O)Nc4cc(Cl)ccc42)N(c2cc(Cl)ccc2F)C3=O)c(OC)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 771455   

TargetE3 ubiquitin-protein ligase Mdm2 [1-111](Human)
Adamed Pharma

US Patent
LigandPNGBDBM771455((3S)-6-chloro-2'-(5-chloro-2- fluorophenyl)-5'-(2...)
Affinity DataKi:  1.70nMAssay Description:Fluorescence polarization experiments were read on Biotek Cytation 5 reader with the 470 nm excitation and 520 nm emission filters for fluorescein. T...More data for this Ligand-Target Pair
Ligand Info
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Date in BDB:
12/29/2025
Entry Details
US Patent