BDBM771580 US12415816, Compound I-6

SMILES CCN1CCN(C(=O)c2cc(NC(=O)c3ccc(C)c(-c4ccc5nc(NC(=O)C6CC6)sc5n4)c3)cc(C(F)(F)F)c2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 771580   

TargetTyrosine-protein kinase JAK2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM771580(US12415816, Compound I-6)
Affinity DataIC50: 1.45E+3nMAssay Description:The JAK2 Z-Lyte biochemical assay was performed according to manufacturer's instructions (Life Technologies).More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent