BDBM771616 US20250092044, Comparative Example C

SMILES Cn1cc(-c2[nH]c3ncc4c(c3c2-c2ccc3c(cnn3C)c2)n([C@H]2CC[C@@H](CC#N)CC2)c(=O)n4C)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 771616   

LigandChemical structure of BindingDB Monomer ID 771616BDBM771616(US20250092044, Comparative Example C)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/31/2025
Entry Details
US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 771616BDBM771616(US20250092044, Comparative Example C)
Affinity DataIC50: 25nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/31/2025
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 771616BDBM771616(US20250092044, Comparative Example C)
Affinity DataIC50: 25nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/31/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 771616BDBM771616(US20250092044, Comparative Example C)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/31/2025
Entry Details
US Patent