BDBM771793 15-chloro-21,23-difluoro-16-hydroxy-12,18,18-trioxo-8,11-dioxa-18lambda6-thia-19-azatetracyclo[18.3.1.113,17.02,7]pentacosa-1(24),2,4,6,13,15,17(25),20,22-nonaene-4-carbonitrile ::US20250289793, Compound 28

SMILES N#Cc1ccc2c(c1)-c1cc(c(F)cc1F)NS(=O)(=O)c1cc(cc(Cl)c1O)C(=O)OCCO2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 771793   

TargetATP-citrate synthase(Human)
Esperion Therapeutics

US Patent
LigandPNGBDBM771793(15-chloro-21,23-difluoro-16-hydroxy-12,18,18-triox...)
Affinity DataIC50: 60nMAssay Description:Table 2: Compounds of the disclosure were evaluated for their efficacy in inhibiting hACLY using rapid fire mass spectrometry (RF/MS). The final reac...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/2/2026
Entry Details
US Patent