BDBM771858 15-chloro-21-fluoro-16-hydroxy-11-methyl-18,18-dioxo-8-oxa-18λ6-thia-11,19-diazatetracyclo[18.3.1.113,17.02,7]pentacosa-1(24),2,4,6,13(25),14,16,20,22-nonaen-10-one ::US20250289793, Compound 93

SMILES CN1Cc2cc(Cl)c(O)c(c2)S(=O)(=O)Nc2cc(ccc2F)-c2ccccc2OCC1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 771858   

TargetATP-citrate synthase(Human)
Esperion Therapeutics

US Patent
LigandPNGBDBM771858(15-chloro-21-fluoro-16-hydroxy-11-methyl-18,18-dio...)
Affinity DataIC50: 60nMAssay Description:Table 2: Compounds of the disclosure were evaluated for their efficacy in inhibiting hACLY using rapid fire mass spectrometry (RF/MS). The final reac...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/2/2026
Entry Details
US Patent