BDBM772337 5-((1-((7-ethyl-6-oxo- 5,6-dihydro-1,5- naphthyridin-3-yl)methyl) azetidin-3-yl)oxy)-3-fluoro- N-methylpicolinamide::US20250289814, Compound 2

SMILES CCc1cc2ncc(CN3CC(Oc4cnc(C(=O)NC)c(I)c4)C3)cc2[nH]c1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 772337   

TargetPoly [ADP-ribose] polymerase 1(Human)
Ningbo Newbay Technology Development Co.

US Patent
LigandPNGBDBM772337(5-((1-((7-ethyl-6-oxo- 5,6-dihydro-1,5- naphthyrid...)
Affinity DataIC50: 7.70nMAssay Description:FP experiments were carried out at room temperature using no-binding black 384-well microplates. Recombinant full length PARP1 and PARP2 proteins pro...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/4/2026
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Ningbo Newbay Technology Development Co.

US Patent
LigandPNGBDBM772337(5-((1-((7-ethyl-6-oxo- 5,6-dihydro-1,5- naphthyrid...)
Affinity DataIC50: 1.00E+4nMAssay Description:FP experiments were carried out at room temperature using no-binding black 384-well microplates. Recombinant full length PARP1 and PARP2 proteins pro...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/4/2026
Entry Details
US Patent