BDBM772340 Step 8: (R)—N—((S)-1-(7-ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)ethyl)-2-methylpropane-2-sulfinamide::US20250289814, Compound 5

SMILES CCc1cc2ncc([C@H](C)N3CC(Oc4ccc(C(=O)NC)nc4)C3)cc2[nH]c1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 772340   

TargetPoly [ADP-ribose] polymerase 1(Human)
Ningbo Newbay Technology Development Co.

US Patent
LigandPNGBDBM772340(Step 8: (R)—N—((S)-1-(7-ethyl-6-oxo-5,6-dihydro-1,...)
Affinity DataIC50: 5.20nMAssay Description:FP experiments were carried out at room temperature using no-binding black 384-well microplates. Recombinant full length PARP1 and PARP2 proteins pro...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/4/2026
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Ningbo Newbay Technology Development Co.

US Patent
LigandPNGBDBM772340(Step 8: (R)—N—((S)-1-(7-ethyl-6-oxo-5,6-dihydro-1,...)
Affinity DataIC50: 3.12E+3nMAssay Description:FP experiments were carried out at room temperature using no-binding black 384-well microplates. Recombinant full length PARP1 and PARP2 proteins pro...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/4/2026
Entry Details
US Patent