BDBM772426 (1R,5S,6s)-tert-butyl 6-(2-(5- (pyridin-3-yl)isoxazole-3- carboxamido)ethyl)-3- azabicyclo[3.1.0]hexane-3- carboxylate::US12421210, Example 12

SMILES CC(C)(C)OC(=O)N1C[C@@H]2[C@@H](CCNC(=O)c3cc(-c4cccnc4)on3)[C@@H]2C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 772426   

TargetNicotinamide phosphoribosyltransferase(Human)
New York University

US Patent
LigandPNGBDBM772426((1R,5S,6s)-tert-butyl 6-(2-(5- (pyridin-3-yl)isoxa...)
Affinity DataIC50: 100nMAssay Description:To test the inhibition activity (IC50) of the compounds of the disclosure against the enzymatic activity of NAMPT, the compounds were dissolved in 10...More data for this Ligand-Target Pair
Ligand Info
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Date in BDB:
1/6/2026
Entry Details
US Patent