BDBM772497 N-(2-((1R,5S,6s)-3-(tert- butylcarbamoyl)-3- azabicyclo[3.1.0]hexan-6-yl)ethyl)- 5-(pyridin-3-yl)isoxazole-3- carboxamide::US12421210, Example 81

SMILES CC(C)(C)NC(=O)N1C[C@@H]2[C@@H](CCNC(=O)c3cc(-c4cccnc4)on3)[C@@H]2C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 772497   

TargetNicotinamide phosphoribosyltransferase(Human)
New York University

US Patent
LigandPNGBDBM772497(N-(2-((1R,5S,6s)-3-(tert- butylcarbamoyl)-3- azabi...)
Affinity DataIC50: 100nMAssay Description:To test the inhibition activity (IC50) of the compounds of the disclosure against the enzymatic activity of NAMPT, the compounds were dissolved in 10...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/6/2026
Entry Details
US Patent