BDBM772590 2-((1R,5S,6s)-6-(2-((E)-3- (pyridin-3- yl)acrylamido)ethyl)-3- azabicyclo[3.1.0]hexan-3- yl)pyrimidine-5- carboxamide::US12421210, Example 174

SMILES NC(=O)c1cnc(N2C[C@@H]3[C@@H](CCNC(=O)/C=C/c4cccnc4)[C@@H]3C2)nc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 772590   

TargetNicotinamide phosphoribosyltransferase(Human)
New York University

US Patent
LigandPNGBDBM772590(2-((1R,5S,6s)-6-(2-((E)-3- (pyridin-3- yl)acrylami...)
Affinity DataIC50: 100nMAssay Description:To test the inhibition activity (IC50) of the compounds of the disclosure against the enzymatic activity of NAMPT, the compounds were dissolved in 10...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/6/2026
Entry Details
US Patent