BDBM772623 N-(2-((1R,5S,6s)-3-(2-chloro-5- fluoropyrimidin-4-yl)-3- azabicyclo[3.1.0]hexan-6-yl)ethyl)- 3-(pyridin-3-yl)propanamide::US12421210, Example 207

SMILES O=C(CCc1cccnc1)NCC[C@@H]1[C@H]2CN(c3nc(Cl)ncc3F)C[C@@H]12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 772623   

TargetNicotinamide phosphoribosyltransferase(Human)
New York University

US Patent
LigandPNGBDBM772623(N-(2-((1R,5S,6s)-3-(2-chloro-5- fluoropyrimidin-4-...)
Affinity DataIC50: 100nMAssay Description:To test the inhibition activity (IC50) of the compounds of the disclosure against the enzymatic activity of NAMPT, the compounds were dissolved in 10...More data for this Ligand-Target Pair
Ligand Info
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Date in BDB:
1/6/2026
Entry Details
US Patent