BDBM772743 (E)-N-(2-((1R,5S,6s)-3- (5-fluoro-2- (methylamino)pyrimidin- 4-yl)-3- azabicyclo[3.1.0]hexan-6- yl)ethyl)-3-(pyridin-3- yl)acrylamide::US12421210, Example 327

SMILES CNc1ncc(F)c(N2C[C@@H]3[C@@H](CCNC(=O)/C=C/c4cccnc4)[C@@H]3C2)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 772743   

TargetNicotinamide phosphoribosyltransferase(Human)
New York University

US Patent
LigandPNGBDBM772743((E)-N-(2-((1R,5S,6s)-3- (5-fluoro-2- (methylamino)...)
Affinity DataIC50: 100nMAssay Description:To test the inhibition activity (IC50) of the compounds of the disclosure against the enzymatic activity of NAMPT, the compounds were dissolved in 10...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/6/2026
Entry Details
US Patent