BDBM774098 N—((S-1-(3-fluoropropyl)pyrrolidin-3-yl)-6-((5S,7R)-7-methyl-6-(2,2,2-trifluoroethyl)-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)pyridin-3-amine 6::US12428428, Example 6

SMILES C[C@@H]1Cc2cc3c(cc2[C@@H](c2ccc(N[C@H]4CCN(CCCF)C4)cn2)N1CC(F)(F)F)OCO3

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 774098   

TargetEstrogen receptor(Human)
Jiangsu Hengrui Medicine Co.

US Patent
LigandPNGBDBM774098(N—((S-1-(3-fluoropropyl)pyrrolidin-3-yl)-6-((5S,7R...)
Affinity DataIC50: 0.270nMAssay Description:An ERE was cloned upstream of the luciferase gene, and MCF-7/ERE-luciferase monoclonal cells were selected by transfection of MCF-7 (TCHu74, National...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent