BDBM7741 4-[N -(1-Chloro-7-oxo-6,7-dihydro-3H-pyrrolo[3,2-e]indazol-8-ylidene)-hydrazino]benzenesulfonamide::4-{2-[(12Z)-3-chloro-11-oxo-4,5,10-triazatricyclo[7.3.0.0^{2,6}]dodeca-1,3,6,8-tetraen-12-ylidene]hydrazin-1-yl}benzene-1-sulfonamide::Oxindole-Based Inhibitor 77

SMILES NS(=O)(=O)c1ccc(cc1)N=Nc1c2c(ccc3[nH][nH]c(Cl)c23)[nH]c1=O

InChI Key InChIKey=LWZGGYIOLDKNFI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 7741   

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM7741(4-[N -(1-Chloro-7-oxo-6,7-dihydro-3H-pyrrolo[3,2-e...)
Affinity DataIC50:  83nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM7741(4-[N -(1-Chloro-7-oxo-6,7-dihydro-3H-pyrrolo[3,2-e...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM7741(4-[N -(1-Chloro-7-oxo-6,7-dihydro-3H-pyrrolo[3,2-e...)
Affinity DataIC50:  83nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM7741(4-[N -(1-Chloro-7-oxo-6,7-dihydro-3H-pyrrolo[3,2-e...)
Affinity DataIC50:  2.20nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed