BDBM774744 N1-(4-(6-(4-aminopiperidin-1-yl)-5-cyano-4-(4-cyano-3-fluorophenyl)pyridin-3-yl)-2-hydroxyphenyl)-N8-hydroxyoctanediamide hydrochloride::US20250304549, Example 58

SMILES N#Cc4ccc(c2c(C#N)c(N1CCC(N)CC1)ncc2c3ccc(NC(=O)CCCCCCC(=O)NO)c(O)c3)cc4F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 774744   

LigandPNGBDBM774744(N1-(4-(6-(4-aminopiperidin-1-yl)-5-cyano-4-(4-cyan...)
Affinity DataIC50: 0.100nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetHistone deacetylase 1/8(Human)TBA
LigandPNGBDBM774744(N1-(4-(6-(4-aminopiperidin-1-yl)-5-cyano-4-(4-cyan...)
Affinity DataIC50: 31.9nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM774744(N1-(4-(6-(4-aminopiperidin-1-yl)-5-cyano-4-(4-cyan...)
Affinity DataIC50: 47.4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetHistone deacetylase 8(Human)TBA
LigandPNGBDBM774744(N1-(4-(6-(4-aminopiperidin-1-yl)-5-cyano-4-(4-cyan...)
Affinity DataIC50: 136nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent