BDBM774789 (E)-3-(5-((1-(3- Cyano-4-(4- cyano-3- fluorophenyl)-5- (3-hydroxy-4- methoxyphenyl) pyridin-2- yl)piperidin-4- yl)amino)methyl) pyridin-2-yl)-N- hydroxyacrylamide formate::US20250304549, Example 117

SMILES COc1ccc(-c2cnc(N3CCC(NCc4ccc(/C=C/C(=O)NO)cc4)CC3)c(C#N)c2-c2ccc(C#N)c(F)c2)cc1O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 774789   

LigandPNGBDBM774789((E)-3-(5-((1-(3- Cyano-4-(4- cyano-3- fluorophenyl...)
Affinity DataIC50: 0.360nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM774789((E)-3-(5-((1-(3- Cyano-4-(4- cyano-3- fluorophenyl...)
Affinity DataIC50: 0.590nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetHistone deacetylase 1/8(Human)TBA
LigandPNGBDBM774789((E)-3-(5-((1-(3- Cyano-4-(4- cyano-3- fluorophenyl...)
Affinity DataIC50: 0.800nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetHistone deacetylase 8(Human)TBA
LigandPNGBDBM774789((E)-3-(5-((1-(3- Cyano-4-(4- cyano-3- fluorophenyl...)
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent