BDBM774802 (E)-3-(4-(((1-(3- Cyano-4-(4- cyano-3- fluorophenyl)-5- (3-hydroxy-4- (hydroxymethyl) phenyl)pyridin-2- yl)piperidin-4- yl)amino)methyl) phenyl)-N- hydroxyacrylamide formate::US20250304549, Example 131

SMILES N#Cc1ccc(-c2c(-c3ccc(CO)c(O)c3)cnc(N3CCC(NCc4ccc(/C=C/C(=O)NO)cc4)CC3)c2C#N)cc1F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 774802   

TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM774802((E)-3-(4-(((1-(3- Cyano-4-(4- cyano-3- fluoropheny...)
Affinity DataIC50: 0.220nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM774802((E)-3-(4-(((1-(3- Cyano-4-(4- cyano-3- fluoropheny...)
Affinity DataIC50: 1.31nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetHistone deacetylase 1/8(Human)TBA
LigandPNGBDBM774802((E)-3-(4-(((1-(3- Cyano-4-(4- cyano-3- fluoropheny...)
Affinity DataIC50: 1.57nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetHistone deacetylase 8(Human)TBA
LigandPNGBDBM774802((E)-3-(4-(((1-(3- Cyano-4-(4- cyano-3- fluoropheny...)
Affinity DataIC50: 46.6nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent