BDBM774805 (E)-3-(4-(((1-(3- Cyano-4-(4- cyano-2- fluorophenyl)-5- (3-hydroxy-4- methoxyphenyl) pyridin-2- yl)piperidin-4- yl)amino)methyl) phenyl)-N- hydroxyacrylamide formate::US20250304549, Example 134

SMILES COc5ccc(c3cnc(N2CCC(NCc1ccc(/C=C/C(=O)NO)cc1)CC2)c(C#N)c3c4ccc(C#N)cc4F)cc5O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 774805   

TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM774805((E)-3-(4-(((1-(3- Cyano-4-(4- cyano-2- fluoropheny...)
Affinity DataIC50: 0.320nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetHistone deacetylase 1/8(Human)TBA
LigandPNGBDBM774805((E)-3-(4-(((1-(3- Cyano-4-(4- cyano-2- fluoropheny...)
Affinity DataIC50: 3.55nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM774805((E)-3-(4-(((1-(3- Cyano-4-(4- cyano-2- fluoropheny...)
Affinity DataIC50: 13.6nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetHistone deacetylase 8(Human)TBA
LigandPNGBDBM774805((E)-3-(4-(((1-(3- Cyano-4-(4- cyano-2- fluoropheny...)
Affinity DataIC50: 46nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent