BDBM774820 (E)-3-(4-(((1-(3- Cyano-5-(3- hydroxy-4- methoxyphenyl)- 4-(4- nitrophenyl) pyridin-2- yl)piperidin-4- yl)amino)methyl) phenyl)-N- hydroxyacrylamide formate::US20250304549, Example 150

SMILES COc1ccc(-c2cnc(N3CCC(NCc4ccc(/C=C/C(=O)NO)cc4)CC3)c(C#N)c2-c2ccc([N+](=O)[O-])cc2)cc1O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 774820   

TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM774820((E)-3-(4-(((1-(3- Cyano-5-(3- hydroxy-4- methoxyph...)
Affinity DataIC50: 0.210nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM774820((E)-3-(4-(((1-(3- Cyano-5-(3- hydroxy-4- methoxyph...)
Affinity DataIC50: 0.590nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetHistone deacetylase 1/8(Human)TBA
LigandPNGBDBM774820((E)-3-(4-(((1-(3- Cyano-5-(3- hydroxy-4- methoxyph...)
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetHistone deacetylase 8(Human)TBA
LigandPNGBDBM774820((E)-3-(4-(((1-(3- Cyano-5-(3- hydroxy-4- methoxyph...)
Affinity DataIC50: 89.3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent