BDBM774847 (E)-3-(2- cyano-4-((1- (3-cyano- 4-(4-cyano-3- fluorophenyl)-5-(3- hydroxy-4- methoxyphenyl) pyridin- 2-yl)piperidin-4- yl)amino)methyl) phenoxy)-N- hydroxyacetamide formate::US20250304549, Example 181

SMILES COc1ccc(-c2cnc(N3CCC(NCc4ccc(OCC(=O)NO)cc4)CC3)c(C#N)c2-c2ccc(C#N)c(F)c2)cc1O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 774847   

TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM774847((E)-3-(2- cyano-4-((1- (3-cyano- 4-(4-cyano-3- flu...)
Affinity DataIC50: 0.0800nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM774847((E)-3-(2- cyano-4-((1- (3-cyano- 4-(4-cyano-3- flu...)
Affinity DataIC50: 0.130nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetHistone deacetylase 1/8(Human)TBA
LigandPNGBDBM774847((E)-3-(2- cyano-4-((1- (3-cyano- 4-(4-cyano-3- flu...)
Affinity DataIC50: 2.11nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetHistone deacetylase 8(Human)TBA
LigandPNGBDBM774847((E)-3-(2- cyano-4-((1- (3-cyano- 4-(4-cyano-3- flu...)
Affinity DataIC50: 75.1nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent