BDBM774877 (E)-3-(4- (((1-(3-Cyano- 4-(4-cyano-3- fluorophenyl)-5-(3- hydroxy-4- methoxyphenyl) pyridin- 2-yl)piperidin-4- yl)amino)methyl)-3- methylphenyl)-N- hydroxyacrylamide formate::US20250304549, Example 211

SMILES COc1ccc(-c2cnc(N3CCC(NCc4ccc(/C=C/C(=O)NO)cc4C)CC3)c(C#N)c2-c2ccc(C#N)c(F)c2)cc1O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 774877   

LigandPNGBDBM774877((E)-3-(4- (((1-(3-Cyano- 4-(4-cyano-3- fluoropheny...)
Affinity DataIC50: 0.310nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetHistone deacetylase 1/8(Human)TBA
LigandPNGBDBM774877((E)-3-(4- (((1-(3-Cyano- 4-(4-cyano-3- fluoropheny...)
Affinity DataIC50: 2.04nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetHistone deacetylase 8(Human)TBA
LigandPNGBDBM774877((E)-3-(4- (((1-(3-Cyano- 4-(4-cyano-3- fluoropheny...)
Affinity DataIC50: 83.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent