BDBM775013 US20250304563, Compound 191
SMILES C[C@H]7CCCN(Cc6cc5C(=O)N(c4cc(C2(Cc1nncn1C)COC2)cc(N[C@@H]3C[C@H](N=[N+]=[N-])C3)n4)Cc5c(C(F)(F)F)c6)C7
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 775013
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Human)
Orum Therapeutics
US Patent
Orum Therapeutics
US Patent
Affinity DataIC50: 12.5nMAssay Description:Compounds were assessed for binding activity to Cbl-b by their ability to compete with and displace a probe comprised of BODIPY-FL fluorophore conjug...More data for this Ligand-Target Pair
Ligand Info
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Human)
Orum Therapeutics
US Patent
Orum Therapeutics
US Patent
Affinity DataIC50: 550nMAssay Description:Compounds were assessed for binding activity to Cbl-b by their ability to compete with and displace a probe comprised of BODIPY-FL fluorophore conjug...More data for this Ligand-Target Pair
Ligand Info
