BDBM775043 US20250304578, Compound Cpd-A

SMILES CNS(=O)c1ccc(NCC#Cc2cc3c(N[C@@H]4CCN(C)C[C@@H]4F)cccc3n2CC(F)(F)F)c(OC)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 775043   

TargetCytochrome P450 3A4/3A5(Human)
Nutshell Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM775043(US20250304578, Compound Cpd-A)
Affinity DataIC50: 890nMAssay Description:Liver microsomes were thawed in a 37° C. water bath prior to use. Liver microsome working solution (final system concentration of 0.5 mg/mL) was prep...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetCytochrome P450 3A4/3A5(Human)
Nutshell Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM775043(US20250304578, Compound Cpd-A)
Affinity DataIC50: 2.30E+3nMAssay Description:Liver microsomes were thawed in a 37° C. water bath prior to use. Liver microsome working solution (final system concentration of 0.5 mg/mL) was prep...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent