BDBM775044 US20250304578, Compound Cpd-B

SMILES COc1cc(S(C)(=O)=O)ccc1NCC#Cc1nc2c(N[C@@H]3CCN(C)C[C@@H]3F)cccn2c1CC(F)(F)F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 775044   

TargetCytochrome P450 3A4/3A5(Human)
Nutshell Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM775044(US20250304578, Compound Cpd-B)
Affinity DataIC50: 3.20E+3nMAssay Description:Liver microsomes were thawed in a 37° C. water bath prior to use. Liver microsome working solution (final system concentration of 0.5 mg/mL) was prep...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetCytochrome P450 3A4/3A5(Human)
Nutshell Therapeutics (Shanghai) Co.

US Patent
LigandPNGBDBM775044(US20250304578, Compound Cpd-B)
Affinity DataIC50: 5.80E+3nMAssay Description:Liver microsomes were thawed in a 37° C. water bath prior to use. Liver microsome working solution (final system concentration of 0.5 mg/mL) was prep...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent