BDBM775049 US20250304585, Compound 3a

SMILES Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2[C@@H]1CCCN(C(=O)CCl)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 775049   

TargetTyrosine-protein kinase BTK(Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775049(US20250304585, Compound 3a)
Affinity DataIC50: 29nMAssay Description:Kinase reactions are assembled in 384-well plates (Greiner) in a total volume of 20 μL. Test compounds (3a-3g) were diluted in DMSO to a final concen...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775049(US20250304585, Compound 3a)
Affinity DataIC50: 261nMAssay Description:Kinase reactions are assembled in 384-well plates (Greiner) in a total volume of 20 μL. Test compounds (3a-3g) were diluted in DMSO to a final concen...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775049(US20250304585, Compound 3a)
Affinity DataIC50: 795nMAssay Description:Kinase reactions are assembled in 384-well plates (Greiner) in a total volume of 20 μL. Test compounds (3a-3g) were diluted in DMSO to a final concen...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent