BDBM775053 US20250304585, Compound 3e

SMILES NC1N=CN=C2C1C(c1ccc(Oc3ccccc3)cc1)=NN2[C@@H]1CCCN(C(=O)COS(=O)(=O)Nc2ccccc2)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 775053   

TargetTyrosine-protein kinase BTK(Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775053(US20250304585, Compound 3e)
Affinity DataIC50: 95nMAssay Description:Kinase reactions are assembled in 384-well plates (Greiner) in a total volume of 20 μL. Test compounds (3a-3g) were diluted in DMSO to a final concen...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775053(US20250304585, Compound 3e)
Affinity DataIC50: 275nMAssay Description:Kinase reactions are assembled in 384-well plates (Greiner) in a total volume of 20 μL. Test compounds (3a-3g) were diluted in DMSO to a final concen...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775053(US20250304585, Compound 3e)
Affinity DataIC50: 1.96E+3nMAssay Description:Kinase reactions are assembled in 384-well plates (Greiner) in a total volume of 20 μL. Test compounds (3a-3g) were diluted in DMSO to a final concen...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent