BDBM775074 US20250304587, Compound 3

SMILES C=CCn1c(=O)c2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc2n1-c1ccc2c(n1)C(C)(O)C1(CC1)C2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 775074   

TargetWee1-like protein kinase(Human)
Jiangsu Tasly Diyi Pharmaceutical Co.

US Patent
LigandPNGBDBM775074(US20250304587, Compound 3)
Affinity DataIC50: 7.5nMAssay Description:WEE1 (Thermo Fisher, Cat #PR7373A) protein in buffer (50 mM HEPES pH 7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% Brij-35) at 15 nM) in different concentration...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Jiangsu Tasly Diyi Pharmaceutical Co.

US Patent
LigandPNGBDBM775074(US20250304587, Compound 3)
Affinity DataIC50: 1.00E+4nMAssay Description:Enzymatic experiments were performed to quantify the inhibition of CYP450 enzyme activity of each isoform of CYP450 by small molecule inhibitors thro...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Jiangsu Tasly Diyi Pharmaceutical Co.

US Patent
LigandPNGBDBM775074(US20250304587, Compound 3)
Affinity DataIC50: 1.00E+4nMAssay Description:Enzymatic experiments were performed to quantify the inhibition of CYP450 enzyme activity of each isoform of CYP450 by small molecule inhibitors thro...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetCytochrome P450 2C8(Human)
Jiangsu Tasly Diyi Pharmaceutical Co.

US Patent
LigandPNGBDBM775074(US20250304587, Compound 3)
Affinity DataIC50: 1.00E+4nMAssay Description:Enzymatic experiments were performed to quantify the inhibition of CYP450 enzyme activity of each isoform of CYP450 by small molecule inhibitors thro...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Jiangsu Tasly Diyi Pharmaceutical Co.

US Patent
LigandPNGBDBM775074(US20250304587, Compound 3)
Affinity DataIC50: 1.00E+4nMAssay Description:Enzymatic experiments were performed to quantify the inhibition of CYP450 enzyme activity of each isoform of CYP450 by small molecule inhibitors thro...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetCytochrome P450 2C19(Human)
Jiangsu Tasly Diyi Pharmaceutical Co.

US Patent
LigandPNGBDBM775074(US20250304587, Compound 3)
Affinity DataIC50: 1.00E+4nMAssay Description:Enzymatic experiments were performed to quantify the inhibition of CYP450 enzyme activity of each isoform of CYP450 by small molecule inhibitors thro...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetCytochrome P450 2C9(Human)
Jiangsu Tasly Diyi Pharmaceutical Co.

US Patent
LigandPNGBDBM775074(US20250304587, Compound 3)
Affinity DataIC50: 1.00E+4nMAssay Description:Enzymatic experiments were performed to quantify the inhibition of CYP450 enzyme activity of each isoform of CYP450 by small molecule inhibitors thro...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent