BDBM775118 1,2-dimethyl-N-(5-((2-(1-methyl-1H-pyrazol-4-yl)pyridin-4-yl)oxy)pyridin-2-yl)-6-oxo-1,6-dihydropyrimidine-5-carboxamide::US12435062, Compound 8

SMILES Cc1ncc(C(=O)Nc2ccc(Oc3ccnc(-c4cnn(C)c4)c3)cn2)c(=O)n1C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 775118   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM775118(1,2-dimethyl-N-(5-((2-(1-methyl-1H-pyrazol-4-yl)py...)
Affinity DataIC50: 4nMAssay Description:1) Kinase reaction (10 μL system)2.5 μL of 4× test compound was added to each reaction well of the 384 plate, and the corresponding volume of 8% DMSO...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/21/2026
Entry Details
US Patent