BDBM775128 US12435062, Compound 48

SMILES Cn1nccc1Nc1cc(Oc2ccc(NC(=O)c3cccn(C)c3=O)nc2)ccn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 775128   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM775128(US12435062, Compound 48)
Affinity DataIC50: 0.00500nMAssay Description:1) Kinase reaction (10 μL system)2.5 μL of 4× test compound was added to each reaction well of the 384 plate, and the corresponding volume of 8% DMSO...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/21/2026
Entry Details
US Patent