BDBM775194 US12435062, Compound 72

SMILES Cn1ccc(-c2cc(Oc3ccc(NC(=O)c4cc5ccccc5n(C)c4=O)nc3)ccn2)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 775194   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM775194(US12435062, Compound 72)
Affinity DataIC50: 0.0140nMAssay Description:1) Kinase reaction (10 μL system)2.5 μL of 4× test compound was added to each reaction well of the 384 plate, and the corresponding volume of 8% DMSO...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/21/2026
Entry Details
US Patent