BDBM77525 US12503453, Compound 63::US12503453, Compound Table3.21

SMILES O=C(NCCC[C@@H](Cc1ccccc1)C(=O)N1CCC(O)(Cn2cnc3c(N4CCOCC4)cccc3c2=O)CC1)c1ccc2c(Cl)c3c(nc2c1)CCCC3

InChI Key InChIKey=CJEQIDHTYVDRBH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 77525   

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 77525BDBM77525(US12503453, Compound Table3.21 | US12503453, Compo...)
Affinity DataIC50: 60nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2026
Entry Details
US Patent