BDBM776071 (S)-(2-(3-(3-chloropyridin-2-yloxy)pyrrolidin-1-yl)-5-(2-fluorophenoxy)phenyl)methanol ::US12435061, Compound 1-270

SMILES OCc1cc(Oc2ccccc2F)ccc1N1CC[C@H](O)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 776071   

LigandPNGBDBM776071((S)-(2-(3-(3-chloropyridin-2-yloxy)pyrrolidin-1-yl...)
Affinity DataIC50: 7.44nMAssay Description:TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent

LigandPNGBDBM776071((S)-(2-(3-(3-chloropyridin-2-yloxy)pyrrolidin-1-yl...)
Affinity DataIC50: 9.39nMAssay Description:TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent