BDBM776128 US12435061, Compound 1-321

SMILES OCc1cc([C@@H](O)c2ccccc2Cl)ccc1N1CC[C@H](Oc2ncccc2F)C1

InChI Key InChIKey=DXMAIYLAZZLEKW-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 776128   

LigandChemical structure of BindingDB Monomer ID 776128BDBM776128(US12435061, Compound 1-321)
Affinity DataIC50: 5.37nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 776128BDBM776128(US12435061, Compound 1-321)
Affinity DataIC50: 12.2nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Kamari Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 776128BDBM776128(US12435061, Compound 1-321)
Affinity DataIC50: 3.73E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent