BDBM780168 1-(5-benzyl-6-methoxy-[1,1'-biphenyl]-3-yl)-N-(3-(1,1-difluoropropyl)phenyl)-3-::US12441689, Compound 121

SMILES CCC(F)(F)c1cccc(NC(=O)C2C(=O)N(c3cc(Cc4ccccc4)c(OC)c(-c4ccccc4)c3)N=C2C)c1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 780168   

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Epivario

US Patent
LigandPNGBDBM780168(1-(5-benzyl-6-methoxy-[1,1'-biphenyl]-3-yl)-N-(3-(...)
Affinity DataIC50: 55nMAssay Description:10 nM of human ACSS2 protein (OriGene Technologies, Inc) was incubated for 90 minutes at 37 C with various compounds' concentrations in a reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details
US Patent