BDBM780233 N-(3-(1,1-difluoroethyl)phenyl)-1-(6-(difluoromethoxy)-[1,1$#8217;-biphenyl]-3-yl)-3-methyl-::US12441689, Compound 186

SMILES Cc1nn(-c2ccc(OC(F)F)c(-c3ccccc3)c2)cc1C(=O)Nc1cccc(C(C)(F)F)c1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 780233   

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Epivario

US Patent
LigandPNGBDBM780233(N-(3-(1,1-difluoroethyl)phenyl)-1-(6-(difluorometh...)
Affinity DataIC50: 55nMAssay Description:10 nM of human ACSS2 protein (OriGene Technologies, Inc) was incubated for 90 minutes at 37 C with various compounds' concentrations in a reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details
US Patent