BDBM780282 N-(3-(1,1-difluoroethyl)phenyl)-2-(4-methoxyphenyl)-5-methylpyrimidine-4-::US12441689, Compound 247

SMILES COc1ccc(-c2ncc(C)c(C(=O)Nc3cccc(C(C)(F)F)c3)n2)cc1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 780282   

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Epivario

US Patent
LigandChemical structure of BindingDB Monomer ID 780282BDBM780282(N-(3-(1,1-difluoroethyl)phenyl)-2-(4-methoxyphenyl...)
Affinity DataIC50: 55nMAssay Description:10 nM of human ACSS2 protein (OriGene Technologies, Inc) was incubated for 90 minutes at 37 C with various compounds' concentrations in a reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details
US Patent