BDBM782096 US12447153, Example 153

SMILES C=CC(=O)N1CCCN(c2nc3c(Nc4ccc(Oc5ccn6ncnc6c5)c(Cl)c4F)ncnc3cc2OC)CC1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 782096   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 782096BDBM782096(US12447153, Example 153)
Affinity DataIC50: 4nMAssay Description:Compound potencies were determined using CisBio's HTRF Kinease-TK assay technology. The kinases were incubated with 250 nM TK-substrate biotin (C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/9/2026
Entry Details
US Patent