BDBM782821 (S)-4-(2-chloro-4-fluorophenyl)-7-(2-methyl-3-oxo-3-(piperidin-1-yl)propyl)-2H-chromen-2-one::US20250326732, Example 18

SMILES C[C@@H](Cc1ccc2c(-c3ccc(F)cc3Cl)cc(=O)oc2c1)C(=O)N1CCCCC1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 782821   

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM782821((S)-4-(2-chloro-4-fluorophenyl)-7-(2-methyl-3-oxo-...)
Affinity DataIC50: 200nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent