BDBM782890 US20250326732, Example 88::ethyl (S)-1-(2-methyl-3-(2-oxo-4-(o-tolyl)-2H-chromen-7-yl)propanoyl)piperidine-3-carboxylate

SMILES CCOC(=O)[C@H]1CCCN(C(=O)C(C)Cc2ccc3c(-c4ccccc4C)cc(=O)oc3c2)C1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 782890   

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM782890(ethyl (S)-1-(2-methyl-3-(2-oxo-4-(o-tolyl)-2H-chro...)
Affinity DataIC50: 90nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent