BDBM782984 (S)-2-(methyl(2-oxo-4-(o-tolyl)-2H-chromen-7-yl)amino)butanoic acid::US20250326732, Example 180

SMILES CC[C@@H](C(=O)O)N(C)c1ccc2c(-c3ccccc3C)cc(=O)oc2c1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 782984   

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM782984((S)-2-(methyl(2-oxo-4-(o-tolyl)-2H-chromen-7-yl)am...)
Affinity DataIC50: 200nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent