BDBM782999 2-(methyl(2-oxo-4-(o-tolyl)-2H-chromen-7-yl)amino)propanamide::US20250326732, Example 195

SMILES Cc1ccccc1-c1cc(=O)oc2cc(N(C)C(C)C(N)=O)ccc12

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 782999   

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM782999(2-(methyl(2-oxo-4-(o-tolyl)-2H-chromen-7-yl)amino)...)
Affinity DataIC50: 50nMAssay Description:The ability of some compounds of the present invention to inhibit POLRMT were determined in a homogeneous TR-FRET Assay using high-throughput screeni...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent